
Janessa Marie Perez-Motlis, MD
Family Medicine
Highlights
Age Groups Seen
- Infants and Toddlers
- Children 2-4
- Children 5 and up
- Teens
- Adults
- Adults 65 and up
Languages
- English
Gender
FemaleAbout
Janessa Perez-Motlis, MD, is a family medicine physician with Prisma Health Family & Internal Medicine–Seneca. Dr. Perez-Motlis earned her medical degree at St. Matthews University School of Medicine and completed her residency in family medicine at the University of Texas. She is board certified in family medicine and provides care for all ages.
Video
Locations
- Prisma Health Family and Internal Medicine – Seneca
- 12016 North Radio Station Road, Seneca, SC 29678
- Get Directions
- Phone: 864-882-6141
- Fax: 864-882-6680
Expertise
Education
- Medical School: St. Matthew's University School of Medicine
- Residency: University of Texas Medical School/Health Science Center, Family Medicine
- Professional School: Davenport University, Masters of Business Administration (MBA)
Board Certifications
- Family Medicine: American Board of Family Medicine
Insurance
- Absolute Total Care - Ambetter
- Absolute Total Care (Centene)
- Aetna
- Aetna Medicare
- Allwell Medicare - Absolute Total Care
- BCBS
- BCBS Blue Essentials
- BCBS PPC
- BCBSSC Blue Reedy Exchange Product (Upstate)
- BCBSSC State Health Plan (PEBA)
- BlueChoice Health Plan
- BlueChoice Medicaid - Healthy Blue
- BlueChoiceMyChoice Advantage
- Carelon Behavioral Health
- Cigna
- Cigna Medicare
- Companion Benefit Alternatives
- CorVel Workers Compensation
- Evernorth Behavioral Health
- FirstHealth (Aetna)
- Healthy Connections
- Humana - Healthy Horizons
- Humana Choice Care
- Humana Medicare
- Liberty Advantage
- Logistics Health
- Magellan
- MedCost
- Medicare (Traditional Fee-for-Service)
- Molina
- Molina Medicaid
- NHC Advantage
- Optum Behavioral Health
- Promise Health Plan
- SC Medicaid Healthy Connections
- Select Health Medicare
- Select Heath (First Choice)
- Spectera
- TriCare
- UnitedHealthcare Medicare Advantage
- Veterans Affairs Community Care Network - VACCN
- Wellcare (Centene)
Reviews
4.9 of 5 stars
810 Ratings, 170 ReviewsThe Patient Satisfaction Rating is derived from patient surveys based on the likelihood to recommend this provider’s office.
- 2 out of 5 starsReviewed on 7/2/2026
Don't act like you care when you don't we are more than just a number we are people we are more than just your paycheck
- 5 out of 5 starsReviewed on 7/1/2026
I am very happy with Dr. Perez-Motlis and her staff.
- 5 out of 5 starsReviewed on 6/28/2026
It was a new patient appointment so mostly about getting acquainted and initiating some follow-ups. Nothing comes to mind for improvements at this time.
- 5 out of 5 starsReviewed on 6/27/2026
None. The staff is great from check in love the receptionist.
- 5 out of 5 starsReviewed on 6/23/2026
Better signage as you're leaving examining rooms to check out and exit. A very big building but well arranged except signage for exiting two and after check out from visit.
- 5 out of 5 starsReviewed on 6/21/2026
It was an excellent visit. I gorgot to ask how to get a same day visit through MyChart.
- 5 out of 5 starsReviewed on 6/21/2026
There's nothing that they could have done any better. I'm so happy with Janessa. I've had emotional and anxiety problems and sometimes it's hindered my well-being, but Janessa has always been there for me and I'm very, very pleased with Prisma Health.
- 5 out of 5 starsReviewed on 6/20/2026
It was all good
- 5 out of 5 starsReviewed on 6/19/2026
Dr. Perez-Motlis is a wonderful doctor and a kind person. I feel very comfortable speaking with her about any health issues I may have. She is always caring and interested in my concerns. Her demeanor is reassuring no matter what health issues I may have.
- 5 out of 5 starsReviewed on 6/27/2026
I was very satisfied with my new patient appointment with Dr. Motlis.
- 5 out of 5 starsReviewed on 6/13/2026
I appreciate the courtesy, respect, and excellent care I receive at Seneca Family And Internal Medicine. I love this doctor. She is caring, kind, listens carefully and goes above and beyond. She always make sure I have needed prescriptions. When the visit was over she took me out to the checkout desk rather than asking someone else to do it. I am a vision, impaired patient and that meant a lot to me. She also provides excellent care to my mom who loves her as well. All of the staff are very professional and courteous. Thank you all so much.
- 5 out of 5 starsReviewed on 6/8/2026
Dr. Motlis is a very caring and professional person. She is an exceptional person, and a kind and informed physician.
- 5 out of 5 starsReviewed on 6/8/2026
Everything was good and fine no complaints thank you
- 5 out of 5 starsReviewed on 6/7/2026
All was done well
- 5 out of 5 starsReviewed on 6/7/2026
Nothing you did good
- 5 out of 5 starsReviewed on 6/9/2026
No thoughts. Dr Motlis has my complete trust.
- 5 out of 5 starsReviewed on 6/6/2026
Outstanding staff and excellent doctor.
- 5 out of 5 starsReviewed on 6/4/2026
They did an amazing job, keep up the good work.
- 5 out of 5 starsReviewed on 6/4/2026
Everything was good Doctor motlis seems to care for her patients.she provides solutions for your best care
- 5 out of 5 starsReviewed on 6/1/2026
The doctor and staff do a great job!
- 5 out of 5 starsReviewed on 5/31/2026
Nothing every thing was great
- 5 out of 5 starsReviewed on 5/26/2026
I can think of nothing in particular that was lacking during this visit.
- 5 out of 5 starsReviewed on 5/26/2026
I always have a great experience at Prisma
- 5 out of 5 starsReviewed on 5/23/2026
This practice is great. No more supprt needed.
- 5 out of 5 starsReviewed on 5/16/2026
Entire staff is pleasant, positive, and professional.
- 5 out of 5 starsReviewed on 5/15/2026
I am very satisfied with the care and professionalism from Dr. Janessa Perez-Motlis. Thank You!
- 5 out of 5 starsReviewed on 5/15/2026
Everything was perfect
- 5 out of 5 starsReviewed on 5/16/2026
You could not have asked a better staff or a more understanding or nice doctor. Greatly appreciated both. Thank you.
- 5 out of 5 starsReviewed on 5/12/2026
All was great!
- 5 out of 5 starsReviewed on 5/12/2026
Dr. Motlis is a very good person and I trust her with my health care. I see no need for improvement.
- 5 out of 5 starsReviewed on 5/10/2026
My first visit at this facility..everything went great!
- 5 out of 5 starsReviewed on 5/7/2026
My needs were all met
- 5 out of 5 starsReviewed on 5/5/2026
Everything was great.
- 4 out of 5 starsReviewed on 5/4/2026
Just keep up the good work. The people seem to know their jobs and our physician is thorough and asks for rebuttal. Keep it up!
- 3 out of 5 starsReviewed on 5/13/2026
put more than one topic in the visit. In other words, One is in the appointment for a cough, the client should be able to ask the doctor about an earache.
- 5 out of 5 starsReviewed on 5/3/2026
Great experience, can't think of anything that I would change.
- 5 out of 5 starsReviewed on 5/2/2026
I don't think there was any improvement needed...I was very satisfied with my experience.
- 5 out of 5 starsReviewed on 5/1/2026
Everything was good.
- 5 out of 5 starsReviewed on 4/27/2026
Everything was perfect and very pleasant.
- 5 out of 5 starsReviewed on 4/25/2026
Love Dr Motlis and staff. I couldn't ask for any better!
- 5 out of 5 starsReviewed on 4/24/2026
Great job!!
- 5 out of 5 starsReviewed on 4/23/2026
Great experience
- 5 out of 5 starsReviewed on 4/20/2026
Everything was great
- 5 out of 5 starsReviewed on 4/23/2026
It's difficult to get someone on the telephone. I realize in this age of AI they are letting it help but I do prefer a person and not having to wait and go through all the menus. This is true of everywhere nowadays though so it's no big deal really
- 5 out of 5 starsReviewed on 4/20/2026
Nothing I can think of. Every visit is handled professionally and very thorough. Extremely pleased with my care.
- 5 out of 5 starsReviewed on 4/19/2026
I thought everyone was wonderful. They have a great team. From the front office, to the nursing staff and my new physician. I'm so blessed to have them taking care of me. My family doctor retired and all of you were recommended to me. Thank you, for welcoming me.
- 5 out of 5 starsReviewed on 4/19/2026
I am very happy with the care received.
- 5 out of 5 starsReviewed on 4/17/2026
Everyone was caring, polite, and professional. I could not have better care anywhere.
- 5 out of 5 starsReviewed on 4/11/2026
All was good, thanks
- 5 out of 5 starsReviewed on 4/11/2026
None... Dr. Motlis & staff are all top notch and professional.
- 5 out of 5 starsReviewed on 4/11/2026
Well I had to wait over 6 months for an appointment. As a nurse myself I know the challenges that office dr's have. Usually shortage of staff. The wait was worth it ! Dr Perez is wonderful!
- 5 out of 5 starsReviewed on 4/5/2026
Everything was good
- 5 out of 5 starsReviewed on 4/4/2026
Love dr motlis
- 5 out of 5 starsReviewed on 4/3/2026
They were very caring and trustworthy.
- 5 out of 5 starsReviewed on 4/1/2026
Everything was great....nothing to change.
- 5 out of 5 starsReviewed on 3/22/2026
Everything went well and they are very friendly..
- 5 out of 5 starsReviewed on 3/19/2026
You guys are great!
- 5 out of 5 starsReviewed on 3/8/2026
All is well at this facility. I can't see any need for improvement
- 5 out of 5 starsReviewed on 3/9/2026
Nothing. Dr. Motlis and her staff are amazing!
- 5 out of 5 starsReviewed on 3/5/2026
Office was great!!
- 5 out of 5 starsReviewed on 3/5/2026
Everything was great ab the visit
- 5 out of 5 starsReviewed on 3/4/2026
I was very satisfied with my visit.
- 5 out of 5 starsReviewed on 3/1/2026
Doctor and staff were great
- 4 out of 5 starsReviewed on 2/24/2026
I was surprised that I was not put on the bed to lay back for more visual examination. Dr. Motlis was very efficient and kind during her interview and offered some important guidance that I needed to hear. Thank you.
- 5 out of 5 starsReviewed on 2/23/2026
Nothing at this time. I feel i have a doctor who cares!
- 5 out of 5 starsReviewed on 2/23/2026
Everyone was very helpful, friendly, and had smiles on their faces. I was not rushed in and out and had all my questions and concerns taken care of. Love the staff here.
- 5 out of 5 starsReviewed on 2/23/2026
I feel well cared for there
- 5 out of 5 starsReviewed on 2/25/2026
Everything went really well and I love Dr Motlis. She's great!
- 3 out of 5 starsReviewed on 2/22/2026
I only had lab work.
- 5 out of 5 starsReviewed on 2/22/2026
Everything was good
- 5 out of 5 starsReviewed on 2/19/2026
None. Great visit.
- 5 out of 5 starsReviewed on 2/17/2026
My doctor took the time to answer my questions and even wrote a few notes on a sticky note for me.
- 5 out of 5 starsReviewed on 2/16/2026
Being treated at this facility is an excellent experience. We have recommended this office to both friends and family. And we'll continue to do so.
- 5 out of 5 starsReviewed on 2/15/2026
Everyone was very respectful and professional, as well as knowledgeable. I appreciate my time in there.
- 5 out of 5 starsReviewed on 2/14/2026
All were friendly, professional and helpful.
- 5 out of 5 starsReviewed on 2/11/2026
I think Dr. Motlis did everything in the best way possible. No suggestions for improvement.
- 5 out of 5 starsReviewed on 2/10/2026
This was only testing my blood, but everyone was very nice and professional.
- 5 out of 5 starsReviewed on 2/8/2026
Excellent experience as usual from Dr Motlis and her staff.
- 5 out of 5 starsReviewed on 2/7/2026
Dr. MOTLIS is phenomenal! Very caring and attentive!
- 5 out of 5 starsReviewed on 2/6/2026
Although Dr. Motlis was totally engaged in our meeting, I did sense a little pressure by the doctor to end the meeting and move on.
- 5 out of 5 starsReviewed on 2/2/2026
All was excellent.
- 5 out of 5 starsReviewed on 1/31/2026
I love my doctor and nurses. They're all so sweet.
- 5 out of 5 starsReviewed on 1/31/2026
Everything was great!
- 5 out of 5 starsReviewed on 1/26/2026
The office staff are very intuned to the patients and our needs!
- 5 out of 5 starsReviewed on 1/26/2026
I can't think of a thing the doctor was very knowledgeable. I am very good. I was very pleased with her. Thanks.
- 5 out of 5 starsReviewed on 1/26/2026
Can't think of anything. Have been very satisfied with all the care that my husband and I have received since coming to the Prisma Health network in the past 2 years.
- 5 out of 5 starsReviewed on 1/25/2026
None known! Everything was as good as it could be.
- 5 out of 5 starsReviewed on 1/21/2026
Excellent
- 5 out of 5 starsReviewed on 1/20/2026
Everything was fine
- 5 out of 5 starsReviewed on 1/19/2026
I can't think of anything. I felt respected & was very at ease.
- 5 out of 5 starsReviewed on 1/17/2026
Dr Motlis is one of the most wonderful doctors I've ever seen. I'm so grateful to find her.
- 5 out of 5 starsReviewed on 1/15/2026
co-ordinated with lab work
- 5 out of 5 starsReviewed on 1/13/2026
Nothing, best Doctor visit I have had
- 5 out of 5 starsReviewed on 1/11/2026
None - everyone and everything was excellent!!!
- 5 out of 5 starsReviewed on 1/6/2026
Nothing, everything was very good.
- 5 out of 5 starsReviewed on 1/2/2026
The staff did a perspective job. This was my fir6time visiting.
- 5 out of 5 starsReviewed on 1/3/2026
Everyone was great.
- 4 out of 5 starsReviewed on 12/28/2025
Dr. Seemed more worried about the time spent in the room than paying attention attention to me.
- 5 out of 5 starsReviewed on 12/22/2025
Love Dr. Motlis. Her nurse was also excellent
- 5 out of 5 starsReviewed on 12/24/2025
I would appreciate if my doctor could call me to go over my lab results.
- 5 out of 5 starsReviewed on 12/24/2025
No problems with trust or respect at this visit.
- 5 out of 5 starsReviewed on 12/19/2025
At this time I cannot think of anything that I would suggest needs to be improved.
- 5 out of 5 starsReviewed on 12/18/2025
The best ever. Thanks for taking care of me !!!
- 5 out of 5 starsReviewed on 12/18/2025
I love the place. Clean,nice people and the provider was outstanding. I really like her and feel comfortable talking with her
- 5 out of 5 starsReviewed on 12/16/2025
The doctor was wonderful, considerate, and helpful. The nurse was very kind, and the check out person was polite and kind. Very good experience.
- 5 out of 5 starsReviewed on 12/15/2025
No improvements to note. Excellent courtesy and professionalism exhibited by Dr and staff
- 5 out of 5 starsReviewed on 12/7/2025
Seeing Dr. Motlis is always special. I can't think of anything that would have improved our visit except maybe more time with her.
- 5 out of 5 starsReviewed on 12/5/2025
Dr. Motlis is wonderful. She is efficient, but thorough and knowledgeable. I never feel rushed. Always feel listened too.
- 5 out of 5 starsReviewed on 12/4/2025
Nothing I can think of, all the staff is professional, knowledgeable and friendly.
- 5 out of 5 starsReviewed on 11/29/2025
It was all good. This was just a quick lab visit so your questions don't fit very well.
- 5 out of 5 starsReviewed on 11/29/2025
Hate everything being done on computer.
- 5 out of 5 starsReviewed on 11/27/2025
As a new patient, I was pleased to notice the doctor did not act rushed and listened.
- 5 out of 5 starsReviewed on 11/27/2025
I have no complaints Dr Motlis her nurses receptionist and staff lab. Everyone is always courteous professional very helpful. I would highly recommend this office to anyone and I have highly recommended it.
- 5 out of 5 starsReviewed on 11/25/2025
Dr. Motlis does an excellent job. I don't see any room for improvement.
- 5 out of 5 starsReviewed on 11/24/2025
Nothing related to the care
- 5 out of 5 starsReviewed on 11/23/2025
Very efficient method of dealing with a UTI via MyChart. Sent message requesting lab test. Test results within an hour. And prescription to pharmacy within 3 hours.
- 5 out of 5 starsReviewed on 11/23/2025
Keep up the great work!! You are doing it all just right!!
- 5 out of 5 starsReviewed on 12/6/2025
very satisfied in the care taken
- 5 out of 5 starsReviewed on 11/24/2025
I'm not leaving this message to tell you how to improve it. I think the office is perfect. They listen to me. They've been helping me for two years. They're kind. They're courteous. I don't think you could ask for a better team.
- 5 out of 5 starsReviewed on 11/24/2025
Your team is great! I'm happy you are all there for me. Thank you!!
- 5 out of 5 starsReviewed on 11/22/2025
Nothing, I felt supported and respected.
- 5 out of 5 starsReviewed on 11/21/2025
Everything went well. I really love Dr. Perez-Motlis!
- 5 out of 5 starsReviewed on 11/20/2025
Nothing everyone one was very courteous and helpful
- 5 out of 5 starsReviewed on 11/17/2025
Everything was great
- 5 out of 5 starsReviewed on 11/16/2025
All care was the best!
- 5 out of 5 starsReviewed on 11/15/2025
Nothing at all. Janessa Perez-Motlis is the Best! She is very professional, friendly, and effective! I feel well cared for under her direction! ??
- 5 out of 5 starsReviewed on 11/10/2025
Nothing. Very positive
- 5 out of 5 starsReviewed on 11/9/2025
Very pleased with my provider and this facility.
- 5 out of 5 starsReviewed on 11/8/2025
None all went very well.
- 5 out of 5 starsReviewed on 11/8/2025
Love this office
- 5 out of 5 starsReviewed on 11/6/2025
Can't think of anything. Very happy with everything.
- 5 out of 5 starsReviewed on 11/2/2025
I was very impressed with the practice. Dr. Motlis took her time and listened attentively to my questions and responses. She offered valid alternatives to my care.
- 5 out of 5 starsReviewed on 10/31/2025
This was my first visit to this practice and I was very pleased with everything. Nothing to add.
- 5 out of 5 starsReviewed on 10/31/2025
Nothing everything is awesome a very nice place for patients to get in and out of the facility.Providing the best care for all patients and new patients
- 5 out of 5 starsReviewed on 10/30/2025
At this writing nothing comes to mind. Felt heard and physician thoughtful about my concerns.
- 5 out of 5 starsReviewed on 10/28/2025
Nothing could make the experience any better; it was great! Dr. Perez-Motlis is by far, the best primary care doctor I have ever had! She listens, does not judge, and remembers details about my care that make me feel special. She is truly the best!
- 5 out of 5 starsReviewed on 10/24/2025
My nurse technician was extremely knowledgeable and professional, 5-Stars! She is a great representative for PRISMA Health and should me commended...!
- 5 out of 5 starsReviewed on 10/23/2025
Nurse and doctor did a great job. Admin staff were very efficient. However, internal doors were visibly dirty. A doctor's office should be clean.
- 5 out of 5 starsReviewed on 10/21/2025
All good
- 5 out of 5 starsReviewed on 10/20/2025
This was just a blood draw but Katie did the draw and she was amazing
- 5 out of 5 starsReviewed on 10/19/2025
Everyone was very nice.
- 5 out of 5 starsReviewed on 10/19/2025
Full trust in Dr Motlis and staff!
- 5 out of 5 starsReviewed on 10/19/2025
Everything was great I had no issues. Dr Motlis was wonderful ?
- 5 out of 5 starsReviewed on 10/21/2025
Everything was great!
- 5 out of 5 starsReviewed on 10/19/2025
Dr. Perez is awesome. She's very friendly, makes you feel very comfortable, and she's very educated in the medical field and helped me out very much. Thank you very much.
- 5 out of 5 starsReviewed on 10/17/2025
Everything was taken care of correctly and I was taken care of well
- 5 out of 5 starsReviewed on 10/16/2025
Nothing, everything was completed thoroughly and professionally..
- 5 out of 5 starsReviewed on 10/16/2025
Wonderful 1st visit. Excellent physician & staff. Highly recommended,
- 2 out of 5 starsReviewed on 10/15/2025
Blood taking on the 13th seem to not have any connection to the appointment on the 16th. I have an appointment on the 16th as a checkup not sure what about I assumed it was in advance to the 16th. For discussion purposes which makes perfect sense. But technician intimated it was not for that. Not sure what the 13th appointment was for; that's up for speculation. I'm thinking I need to use a different office or physician attendant.
- 5 out of 5 starsReviewed on 10/14/2025
Called me by name.
- 5 out of 5 starsReviewed on 10/14/2025
Dr Motlis and her nurse were wonderful
- 5 out of 5 starsReviewed on 10/12/2025
Nothing the visit was awesome everyone was great
- 5 out of 5 starsReviewed on 10/12/2025
Found a way to get in quicker to see her. I ended up seeing her about a month earlier as I was on the waiting list and kept trying to get in but it was like jumping through hoops to finally get in. She is an excellent doctor and I understand why she has a wait list but this was a bit much
- 5 out of 5 starsReviewed on 10/10/2025
Nothing comes to mind. It just took a long time to get this appointment.
- 5 out of 5 starsReviewed on 10/5/2025
Everything necessary was done.
- 5 out of 5 starsReviewed on 10/3/2025
Everything went well. I have no concerns at this time.
- 5 out of 5 starsReviewed on 10/3/2025
More scheduling flexibility...wanted the appointment later in year but nothing available for 3 months
- 5 out of 5 starsReviewed on 10/2/2025
I don't think there's any thing that I would change for the first visit to the Dr everyone was great.
- 5 out of 5 starsReviewed on 10/2/2025
I was seen for concerns regarding an ongoing illness and breathing concerns. My O2 was not checked nor were my throat, nose, or ears.
- 5 out of 5 starsReviewed on 9/30/2025
Very good first visit. Everyone were courteous and helpful. The only thing that I could offer for improvement is quicker appointment with the Dr. If possible.
- 5 out of 5 starsReviewed on 9/24/2025
Excellent care
- 5 out of 5 starsReviewed on 9/21/2025
No improvements needed. I was very happy with my visit.
- 5 out of 5 starsReviewed on 9/20/2025
I have all the faith in the world in my healthcare Doctor. She always listens to what I have to say and I would not go to anyone else for my care. The dr. and her staff are always pleasant and make sure I didn't forget anything.
- 5 out of 5 starsReviewed on 9/19/2025
I can't think of anything else that could have made my visit any better or easier. Dr. Perez-Motlis is absolutely wonderful! As were her nurses. I am 100% satisfied with my visit.
- 5 out of 5 starsReviewed on 9/18/2025
Your practice is wonderful!!! Dr. Motlis is my doctor and she is the best! Professional, knowledgeable, caring, and always on top of my health condition. I have recommended her to many of my friends!!!
- 5 out of 5 starsReviewed on 9/15/2025
Take s little more time not much though
- 5 out of 5 starsReviewed on 9/12/2025
Excellent
- 5 out of 5 starsReviewed on 9/11/2025
It was very good I felt like she actually listened
- 5 out of 5 starsReviewed on 9/9/2025
None - Dr. Motlis was great!
- 2 out of 5 starsReviewed on 9/8/2025
How about make it affordable?